Just remember, that if you need RStudio (or anything that links against the x86_64 R dylib) you’re going to be reverting this to get stuff done. > One of my grad students has compiled and has running Ambertools21 and AMBER20 on Mac M1 (arm64). Parallels Desktop for Mac Pro Edition is the easiest and most powerful application to run Windows on Mac for developers, testers and experienced power users.Re: Native build for Mac M1 / Darwin ARM64 / Apple Silicon? « Reply #2 on: January 06, 2021, 03:28:24 am » Quote from: Bumber on January 05, 2021, 12:40:14 am.Arm64 mac m1 and study Mac malware, it would.